Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver

We herein report a 48-year-old healthy woman who visited our hospital to investigate a 25-mm space-occupying lesion in the liver. The tumor was irregularly shaped and exhibited heterogeneous enhancement on dynamic computed tomography (CT). Whole-body positron emission tomography-CT showed an abnorma...

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Autores principales: Ogasawara, Nobuhiko, Saitoh, Satoshi, Denpou, Hideyuki, Kinowaki, Keiichi, Akuta, Norio, Suzuki, Fumitaka, Hashimoto, Masashi, Fujiyama, Shunichiro, Kawamura, Yusuke, Sezaki, Hitomi, Hosaka, Tetsuya, Kobayashi, Masahiro, Suzuki, Yoshiyuki, Arase, Yasuji, Ikeda, Kenji, Fujii, Takeshi, Kumada, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028417/
https://www.ncbi.nlm.nih.gov/pubmed/31619599
http://dx.doi.org/10.2169/internalmedicine.3577-19
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author Ogasawara, Nobuhiko
Saitoh, Satoshi
Denpou, Hideyuki
Kinowaki, Keiichi
Akuta, Norio
Suzuki, Fumitaka
Hashimoto, Masashi
Fujiyama, Shunichiro
Kawamura, Yusuke
Sezaki, Hitomi
Hosaka, Tetsuya
Kobayashi, Masahiro
Suzuki, Yoshiyuki
Arase, Yasuji
Ikeda, Kenji
Fujii, Takeshi
Kumada, Hiromitsu
author_facet Ogasawara, Nobuhiko
Saitoh, Satoshi
Denpou, Hideyuki
Kinowaki, Keiichi
Akuta, Norio
Suzuki, Fumitaka
Hashimoto, Masashi
Fujiyama, Shunichiro
Kawamura, Yusuke
Sezaki, Hitomi
Hosaka, Tetsuya
Kobayashi, Masahiro
Suzuki, Yoshiyuki
Arase, Yasuji
Ikeda, Kenji
Fujii, Takeshi
Kumada, Hiromitsu
author_sort Ogasawara, Nobuhiko
collection PubMed
description We herein report a 48-year-old healthy woman who visited our hospital to investigate a 25-mm space-occupying lesion in the liver. The tumor was irregularly shaped and exhibited heterogeneous enhancement on dynamic computed tomography (CT). Whole-body positron emission tomography-CT showed an abnormal fluorodeoxyglucose uptake in the liver tumor, with a maximum standardized uptake value of 12.82. During the ensuing three months, the tumor grew rapidly and the serum alpha-fetoprotein levels also rose; partial hepatectomy was therefore performed. Microscopic findings revealed a moderately-to-poorly differentiated hepatocellular carcinoma in the normal liver.
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spelling pubmed-70284172020-02-26 Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver Ogasawara, Nobuhiko Saitoh, Satoshi Denpou, Hideyuki Kinowaki, Keiichi Akuta, Norio Suzuki, Fumitaka Hashimoto, Masashi Fujiyama, Shunichiro Kawamura, Yusuke Sezaki, Hitomi Hosaka, Tetsuya Kobayashi, Masahiro Suzuki, Yoshiyuki Arase, Yasuji Ikeda, Kenji Fujii, Takeshi Kumada, Hiromitsu Intern Med Case Report We herein report a 48-year-old healthy woman who visited our hospital to investigate a 25-mm space-occupying lesion in the liver. The tumor was irregularly shaped and exhibited heterogeneous enhancement on dynamic computed tomography (CT). Whole-body positron emission tomography-CT showed an abnormal fluorodeoxyglucose uptake in the liver tumor, with a maximum standardized uptake value of 12.82. During the ensuing three months, the tumor grew rapidly and the serum alpha-fetoprotein levels also rose; partial hepatectomy was therefore performed. Microscopic findings revealed a moderately-to-poorly differentiated hepatocellular carcinoma in the normal liver. The Japanese Society of Internal Medicine 2019-10-17 2020-02-01 /pmc/articles/PMC7028417/ /pubmed/31619599 http://dx.doi.org/10.2169/internalmedicine.3577-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ogasawara, Nobuhiko
Saitoh, Satoshi
Denpou, Hideyuki
Kinowaki, Keiichi
Akuta, Norio
Suzuki, Fumitaka
Hashimoto, Masashi
Fujiyama, Shunichiro
Kawamura, Yusuke
Sezaki, Hitomi
Hosaka, Tetsuya
Kobayashi, Masahiro
Suzuki, Yoshiyuki
Arase, Yasuji
Ikeda, Kenji
Fujii, Takeshi
Kumada, Hiromitsu
Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title_full Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title_fullStr Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title_full_unstemmed Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title_short Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver
title_sort poorly differentiated hepatocellular carcinoma in a low-risk patient with an otherwise normal liver
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028417/
https://www.ncbi.nlm.nih.gov/pubmed/31619599
http://dx.doi.org/10.2169/internalmedicine.3577-19
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