A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma

A 77-year-old man with a history of hypertension, prostate hyperplasia, and urolithiasis was admitted for acute kidney injury caused by hypercalcemia. Neck ultrasonography showed a large cyst adjacent to the right lower thyroid lobe. Although a (99m)technetium sestamibi scan was negative, an extreme...

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Detalles Bibliográficos
Autores principales: Uehara, Atsuko, Suzuki, Tomo, Yamamoto, Yutaro, Hasegawa, Masataka, Koitabashi, Kenichiro, Yazawa, Masahiko, Koike, Junki, Shibagaki, Yugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028428/
https://www.ncbi.nlm.nih.gov/pubmed/31588082
http://dx.doi.org/10.2169/internalmedicine.3319-19
Descripción
Sumario:A 77-year-old man with a history of hypertension, prostate hyperplasia, and urolithiasis was admitted for acute kidney injury caused by hypercalcemia. Neck ultrasonography showed a large cyst adjacent to the right lower thyroid lobe. Although a (99m)technetium sestamibi scan was negative, an extremely high intracystic intact parathyroid hormone level suggested that the cyst had a parathyroid origin and that a functional parathyroid cyst was present. Immunohistochemical staining for the calcium-sensing receptor (CaSR) after right lower parathyroidectomy revealed CaSR-positive cells lining the cyst, indicating that the functional parathyroid cyst had originated from the hemorrhagic degeneration of a parathyroid adenoma.

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