A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma

A 77-year-old man with a history of hypertension, prostate hyperplasia, and urolithiasis was admitted for acute kidney injury caused by hypercalcemia. Neck ultrasonography showed a large cyst adjacent to the right lower thyroid lobe. Although a (99m)technetium sestamibi scan was negative, an extreme...

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Autores principales: Uehara, Atsuko, Suzuki, Tomo, Yamamoto, Yutaro, Hasegawa, Masataka, Koitabashi, Kenichiro, Yazawa, Masahiko, Koike, Junki, Shibagaki, Yugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028428/
https://www.ncbi.nlm.nih.gov/pubmed/31588082
http://dx.doi.org/10.2169/internalmedicine.3319-19
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author Uehara, Atsuko
Suzuki, Tomo
Yamamoto, Yutaro
Hasegawa, Masataka
Koitabashi, Kenichiro
Yazawa, Masahiko
Koike, Junki
Shibagaki, Yugo
author_facet Uehara, Atsuko
Suzuki, Tomo
Yamamoto, Yutaro
Hasegawa, Masataka
Koitabashi, Kenichiro
Yazawa, Masahiko
Koike, Junki
Shibagaki, Yugo
author_sort Uehara, Atsuko
collection PubMed
description A 77-year-old man with a history of hypertension, prostate hyperplasia, and urolithiasis was admitted for acute kidney injury caused by hypercalcemia. Neck ultrasonography showed a large cyst adjacent to the right lower thyroid lobe. Although a (99m)technetium sestamibi scan was negative, an extremely high intracystic intact parathyroid hormone level suggested that the cyst had a parathyroid origin and that a functional parathyroid cyst was present. Immunohistochemical staining for the calcium-sensing receptor (CaSR) after right lower parathyroidectomy revealed CaSR-positive cells lining the cyst, indicating that the functional parathyroid cyst had originated from the hemorrhagic degeneration of a parathyroid adenoma.
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spelling pubmed-70284282020-02-26 A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma Uehara, Atsuko Suzuki, Tomo Yamamoto, Yutaro Hasegawa, Masataka Koitabashi, Kenichiro Yazawa, Masahiko Koike, Junki Shibagaki, Yugo Intern Med Case Report A 77-year-old man with a history of hypertension, prostate hyperplasia, and urolithiasis was admitted for acute kidney injury caused by hypercalcemia. Neck ultrasonography showed a large cyst adjacent to the right lower thyroid lobe. Although a (99m)technetium sestamibi scan was negative, an extremely high intracystic intact parathyroid hormone level suggested that the cyst had a parathyroid origin and that a functional parathyroid cyst was present. Immunohistochemical staining for the calcium-sensing receptor (CaSR) after right lower parathyroidectomy revealed CaSR-positive cells lining the cyst, indicating that the functional parathyroid cyst had originated from the hemorrhagic degeneration of a parathyroid adenoma. The Japanese Society of Internal Medicine 2019-10-07 2020-02-01 /pmc/articles/PMC7028428/ /pubmed/31588082 http://dx.doi.org/10.2169/internalmedicine.3319-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Uehara, Atsuko
Suzuki, Tomo
Yamamoto, Yutaro
Hasegawa, Masataka
Koitabashi, Kenichiro
Yazawa, Masahiko
Koike, Junki
Shibagaki, Yugo
A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title_full A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title_fullStr A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title_full_unstemmed A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title_short A Functional Parathyroid Cyst from the Hemorrhagic Degeneration of a Parathyroid Adenoma
title_sort functional parathyroid cyst from the hemorrhagic degeneration of a parathyroid adenoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028428/
https://www.ncbi.nlm.nih.gov/pubmed/31588082
http://dx.doi.org/10.2169/internalmedicine.3319-19
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