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High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer

PURPOSE: This trial aimed to demonstrate the feasibility of high-intensity interval training (HIIT) in postmenopausal, overweight/obese women at high risk of invasive breast cancer and to explore HIIT on changes in cardiorespiratory fitness (CRF), body weight, and body mass index (BMI) compared with...

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Autores principales: COLETTA, ADRIANA M., BREWSTER, ABENAA M., CHEN, MINXING, LI, YISHENG, BEVERS, THERESE B., BASEN-ENGQUIST, KAREN, GILCHRIST, SUSAN C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028472/
https://www.ncbi.nlm.nih.gov/pubmed/31269007
http://dx.doi.org/10.1249/MSS.0000000000002048
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author COLETTA, ADRIANA M.
BREWSTER, ABENAA M.
CHEN, MINXING
LI, YISHENG
BEVERS, THERESE B.
BASEN-ENGQUIST, KAREN
GILCHRIST, SUSAN C.
author_facet COLETTA, ADRIANA M.
BREWSTER, ABENAA M.
CHEN, MINXING
LI, YISHENG
BEVERS, THERESE B.
BASEN-ENGQUIST, KAREN
GILCHRIST, SUSAN C.
author_sort COLETTA, ADRIANA M.
collection PubMed
description PURPOSE: This trial aimed to demonstrate the feasibility of high-intensity interval training (HIIT) in postmenopausal, overweight/obese women at high risk of invasive breast cancer and to explore HIIT on changes in cardiorespiratory fitness (CRF), body weight, and body mass index (BMI) compared with moderate-intensity continuous training (MICT) and usual care (UC). METHODS: Forty-four women were randomized to HIIT, MICT, or UC for a 12-wk, thrice weekly, supervised exercise intervention. HIIT included a 5-min warm-up at 50%–70% HR(peak), four cycles of 4 min at 90%–100% HR(peak), followed by 3 min at 50%–70% HR(peak). MICT consisted of 41 min at 60%–70% HR(peak). Feasibility was assessed by consent, adherence, compliance, and retention rates. CRF, body weight, and BMI were measured at baseline and end of study. Repeated-measures linear mixed models were used to assess within- and between-group differences. RESULTS: Average age was 63.9 ± 8.8 yr. BMI was 30.9 ± 5.7 kg·m(−2). Participants completed 90% and 89% of HIIT and MICT workouts, respectively, with 100% compliance to the exercise prescriptions. No serious adverse events were reported. Compared with MICT and UC, HIIT exhibited improvements in change in treadmill time (101 s greater than MICT, and 125 s greater than UC, respectively, P < 0.001). Compared with UC, HIIT exhibited improvement in changes in absolute and relative V˙O(2peak) (a 0.15-L·min(−1) increase, P = 0.005, and a 2.3-mL·kg(−1)⋅min(−1) increase, P = 0.004). There were no significant differences between groups for body weight or BMI (P > 0.05). CONCLUSIONS: HIIT is feasible, safe, and seems to promote greater improvements in CRF compared with MICT and UC in women at high risk for breast cancer.
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spelling pubmed-70284722020-03-10 High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer COLETTA, ADRIANA M. BREWSTER, ABENAA M. CHEN, MINXING LI, YISHENG BEVERS, THERESE B. BASEN-ENGQUIST, KAREN GILCHRIST, SUSAN C. Med Sci Sports Exerc Clinical Sciences PURPOSE: This trial aimed to demonstrate the feasibility of high-intensity interval training (HIIT) in postmenopausal, overweight/obese women at high risk of invasive breast cancer and to explore HIIT on changes in cardiorespiratory fitness (CRF), body weight, and body mass index (BMI) compared with moderate-intensity continuous training (MICT) and usual care (UC). METHODS: Forty-four women were randomized to HIIT, MICT, or UC for a 12-wk, thrice weekly, supervised exercise intervention. HIIT included a 5-min warm-up at 50%–70% HR(peak), four cycles of 4 min at 90%–100% HR(peak), followed by 3 min at 50%–70% HR(peak). MICT consisted of 41 min at 60%–70% HR(peak). Feasibility was assessed by consent, adherence, compliance, and retention rates. CRF, body weight, and BMI were measured at baseline and end of study. Repeated-measures linear mixed models were used to assess within- and between-group differences. RESULTS: Average age was 63.9 ± 8.8 yr. BMI was 30.9 ± 5.7 kg·m(−2). Participants completed 90% and 89% of HIIT and MICT workouts, respectively, with 100% compliance to the exercise prescriptions. No serious adverse events were reported. Compared with MICT and UC, HIIT exhibited improvements in change in treadmill time (101 s greater than MICT, and 125 s greater than UC, respectively, P < 0.001). Compared with UC, HIIT exhibited improvement in changes in absolute and relative V˙O(2peak) (a 0.15-L·min(−1) increase, P = 0.005, and a 2.3-mL·kg(−1)⋅min(−1) increase, P = 0.004). There were no significant differences between groups for body weight or BMI (P > 0.05). CONCLUSIONS: HIIT is feasible, safe, and seems to promote greater improvements in CRF compared with MICT and UC in women at high risk for breast cancer. Lippincott Williams & Wilkins 2019-11 2019-06-20 /pmc/articles/PMC7028472/ /pubmed/31269007 http://dx.doi.org/10.1249/MSS.0000000000002048 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Sports Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Clinical Sciences
COLETTA, ADRIANA M.
BREWSTER, ABENAA M.
CHEN, MINXING
LI, YISHENG
BEVERS, THERESE B.
BASEN-ENGQUIST, KAREN
GILCHRIST, SUSAN C.
High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title_full High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title_fullStr High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title_full_unstemmed High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title_short High-Intensity Interval Training Is Feasible in Women at High Risk for Breast Cancer
title_sort high-intensity interval training is feasible in women at high risk for breast cancer
topic Clinical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028472/
https://www.ncbi.nlm.nih.gov/pubmed/31269007
http://dx.doi.org/10.1249/MSS.0000000000002048
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