Both JNK1 and JNK2 Are Indispensable for Sensitized Extracellular Matrix Mineralization in IKKβ-Deficient Osteoblasts

Extracellular matrix mineralization is critical for osteogenesis, and its dysregulation could result in osteoporosis and vascular calcification. IKK/NF-κB activation inhibits differentiation of osteoblasts, and reduces extracellular matrix mineralization, however the underlying mechanisms are poorly...

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Detalles Bibliográficos
Autores principales: Hao, Qianyun, Liu, Zhuangzhuang, Lu, Liaoxun, Zhang, Lichen, Zuo, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028708/
https://www.ncbi.nlm.nih.gov/pubmed/32117051
http://dx.doi.org/10.3389/fendo.2020.00013

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