Cargando…

Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo

Ameliorating bone loss caused by mechanical unloading is a substantial clinical challenge, and the role of noncoding RNAs in this process has attracted increasing attention. In this study, we found that the long noncoding RNA osteoblast differentiation-related lncRNA under simulated microgravity (ln...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yixuan, Wang, Ke, Zhang, Lijun, Tan, Yingjun, Hu, Zebing, Dang, Lei, Zhou, Hua, Li, Gaozhi, Wang, Han, Zhang, Shu, Shi, Fei, Cao, Xinsheng, Zhang, Ge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028725/ https://www.ncbi.nlm.nih.gov/pubmed/32071307 http://dx.doi.org/10.1038/s41419-020-2325-3

Ejemplares similares

MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM
por: Wang, Yixuan, et al.
Publicado: (2018)

Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip
por: Zhang, Lijun, et al.
Publicado: (2022)

Circulating Exosomes from Mice with LPS-Induced Bone Loss Inhibit Osteoblast Differentiation
por: Wang, Yixuan, et al.
Publicado: (2022)

Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis
por: Wang, Ke, et al.
Publicado: (2020)

Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice
por: Hu, Zebing, et al.
Publicado: (2020)

Genome-wide analysis and prediction of functional long noncoding RNAs in osteoblast differentiation under simulated microgravity
por: Hu, Zebing, et al.
Publicado: (2017)

The combined effects of simulated microgravity and X-ray radiation on MC3T3-E1 cells and rat femurs
por: Dong, Jingjing, et al.
Publicado: (2021)

Osteoblast-targeted delivery of miR-33-5p attenuates osteopenia development induced by mechanical unloading in mice
por: Wang, Han, et al.
Publicado: (2018)

Bioinformatic analysis of the RNA expression patterns in microgravity-induced bone loss
por: Zhang, Xiaoyan, et al.
Publicado: (2022)

HDAC6 Negatively Regulates miR-155-5p Expression to Elicit Proliferation by Targeting RHEB in Microvascular Endothelial Cells under Mechanical Unloading
por: Xu, Liqun, et al.
Publicado: (2021)

miRNA-132-3p inhibits osteoblast differentiation by targeting Ep300 in simulated microgravity
por: Hu, Zebing, et al.
Publicado: (2015)

miR‐181c‐5p mediates simulated microgravity‐induced impaired osteoblast proliferation by promoting cell cycle arrested in the G(2) phase
por: Sun, Zhongyang, et al.
Publicado: (2019)

miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2
por: Wang, Han, et al.
Publicado: (2016)

Exosomes from Microvascular Endothelial Cells under Mechanical Unloading Inhibit Osteogenic Differentiation via miR-92b-3p/ELK4 Axis
por: Zhang, Xiaoyan, et al.
Publicado: (2022)

Simulated microgravity inhibits L-type calcium channel currents partially by the up-regulation of miR-103 in MC3T3-E1 osteoblasts
por: Sun, Zhongyang, et al.
Publicado: (2015)

MiR‐103‐3p targets the m(6)A methyltransferase METTL14 to inhibit osteoblastic bone formation
por: Sun, Zhongyang, et al.
Publicado: (2021)

Osteoblast-Targeted Overexpression of TAZ Increases Bone Mass In Vivo
por: Yang, Jae-Yeon, et al.
Publicado: (2013)

Vitamin K2 Can Rescue the Dexamethasone-Induced Downregulation of Osteoblast Autophagy and Mitophagy Thereby Restoring Osteoblast Function In Vitro and In Vivo
por: Chen, Liang, et al.
Publicado: (2020)

Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis
por: Moriishi, Takeshi, et al.
Publicado: (2011)

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures
por: Liu, Wenguang, et al.
Publicado: (2001)

Overexpression of Long Noncoding RNA LBX2-AS1 Promotes the Proliferation of Colorectal Cancer
por: Li, Qing, et al.
Publicado: (2021)

Overexpression of CRABP2 inhibits dexamethasone-induced apoptosis in human osteoblast cells
por: Zhang, Haiping, et al.
Publicado: (2021)

Overexpressed Claudin-1 Can Be Visualized Endoscopically in Colonic Adenomas In Vivo
por: Rabinsky, Emily F., et al.
Publicado: (2015)

Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression
por: Wang, Lili, et al.
Publicado: (2018)

Overexpression of Neurogenin 1 Negatively Regulates Osteoclast and Osteoblast Differentiation
por: Kim, Jung Ha, et al.
Publicado: (2022)

Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer
por: Wang, Yang, et al.
Publicado: (2018)

Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo
por: Wang, Shengran, et al.
Publicado: (2023)

Influence of Ceramic Debris on Osteoblast Behaviors: An In Vivo Study
por: Sun, Guo‐jing, et al.
Publicado: (2019)

Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing
por: Auh, Q-Schick, et al.
Publicado: (2016)

Noncoding RNAs-mediated overexpression of KIF14 is associated with tumor immune infiltration and unfavorable prognosis in lung adenocarcinoma
por: Wang, Hong, et al.
Publicado: (2022)

Decoding Noncoding RNAs: Role of MicroRNAs and Long Noncoding RNAs in Ocular Neovascularization
por: Zhang, Yan, et al.
Publicado: (2017)

Meteorin-Like Shows Unique Expression Pattern in Bone and Its Overexpression Inhibits Osteoblast Differentiation
por: Gong, Weiyan, et al.
Publicado: (2016)

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans
por: Liu, Huijie, et al.
Publicado: (2012)

Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation
por: Liu, Tielong, et al.
Publicado: (2015)

Differential Expression Profiling of Long Noncoding RNA and mRNA during Osteoblast Differentiation in Mouse
por: Kim, Minjung, et al.
Publicado: (2018)

A systematic dissection of human primary osteoblasts in vivo at single-cell resolution
por: Gong, Yun, et al.
Publicado: (2021)

Overexpression of PIK3R1 Promotes Bone Formation by Regulating Osteoblast Differentiation and Osteoclast Formation
por: Zhu, Haitao, et al.
Publicado: (2021)

IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway
por: Liu, Zongtao, et al.
Publicado: (2020)

Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling
por: WANG, GUANGYE, et al.
Publicado: (2015)

Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
por: Wang, Lijun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1hcnoueaa2pn4kde35s16t2onr