Mutational Screening of BRCA1/2 Genes as a Predictive Factor for Therapeutic Response in Epithelial Ovarian Cancer: A Consensus Guide from the Spanish Society of Pathology (SEAP-IAP) and the Spanish Society of Human Genetics (AEGH)

Germline/somatic BRCA-mutated ovarian carcinomas (OC) are associated to have better response with platinum-based chemotherapy and long-term prognosis than non-BRCA-associated OCs. In addition, these mutations are predictive factors to response to Poly(ADP-ribose) polymerase (PARP) inhibitors. Differ...

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Detalles Bibliográficos
Autores principales: Palacios, J., de la Hoya, M., Bellosillo, B., de Juan, I., Matías-Guiu, X., Lázaro, C., Palanca, S., Osorio, A., Rojo, F., Rosa-Rosa, J.M., Cigudosa, J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review and Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028830/
https://www.ncbi.nlm.nih.gov/pubmed/31797087
http://dx.doi.org/10.1007/s00428-019-02709-3

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