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SIRT3, PP2A and TTP protein stability in the presence of TNF‐α on vincristine‐induced apoptosis of leukaemia cells

The contribution of vincristine (VCR)‐induced microtubule destabilization to evoke apoptosis in cancer cells remains to be resolved. Thus, we investigated the cytotoxic mechanism of VCR on U937 and HL‐60 human leukaemia cell lines. We discovered that VCR treatment resulted in the up‐regulation of TN...

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Detalles Bibliográficos
Autores principales:	Wang, Liang‐Jun, Chiou, Jing‐Ting, Lee, Yuan‐Chin, Huang, Chia‐Hui, Shi, Yi‐Jun, Chang, Long‐Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028858/ https://www.ncbi.nlm.nih.gov/pubmed/31930676 http://dx.doi.org/10.1111/jcmm.14949

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