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High‐fat diet‐induced dysbiosis mediates MCP‐1/CCR2 axis‐dependent M2 macrophage polarization and promotes intestinal adenoma‐adenocarcinoma sequence

High‐fat diet (HFD) is a well‐known risk factor for gut microbiota dysbiosis and colorectal cancer (CRC). However, evidence relating HFD, gut microbiota and carcinogenesis is limited. Our study aimed to demonstrate that HFD‐induced gut dysbiosis promoted intestinal adenoma‐adenocarcinoma sequence. I...

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Detalles Bibliográficos
Autores principales:	Liu, Tianyu, Guo, Zixuan, Song, Xueli, Liu, Li, Dong, Wenxiao, Wang, Sinan, Xu, Mengque, Yang, Cheng, Wang, Bangmao, Cao, Hailong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028862/ https://www.ncbi.nlm.nih.gov/pubmed/31957197 http://dx.doi.org/10.1111/jcmm.14984

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