Cargando…

Cardiac telocytes exist in the adult Xenopus tropicalis heart

Recent research has revealed that cardiac telocytes (CTs) play an important role in cardiac physiopathology and the regeneration of injured myocardium. Recently, we reported that the adult Xenopus tropicalis heart can regenerate perfectly in a nearly scar‐free manner after injury via apical resectio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Luocheng, Liao, Zhaofu, Luo, Jiali, Chen, Hongyi, Guo, Hongyan, Yang, Jifeng, Huang, Ruijin, Pu, Qin, Zhao, Hui, Yuan, Ziqiang, Feng, Shanshan, Qi, Xufeng, Cai, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028868/
https://www.ncbi.nlm.nih.gov/pubmed/31930692
http://dx.doi.org/10.1111/jcmm.14947
Descripción
Sumario:Recent research has revealed that cardiac telocytes (CTs) play an important role in cardiac physiopathology and the regeneration of injured myocardium. Recently, we reported that the adult Xenopus tropicalis heart can regenerate perfectly in a nearly scar‐free manner after injury via apical resection. However, whether telocytes exist in the X tropicalis heart and are affected in the regeneration of injured X tropicalis myocardium is still unknown. The present ultrastructural and immunofluorescent double staining results clearly showed that CTs exist in the X tropicalis myocardium. CTs in the X tropicalis myocardium were mainly twined around the surface of cardiomyocyte trabeculae and linked via nanocontacts between the ends of the telopodes, forming a three‐dimensional network. CTs might play a role in the regeneration of injured myocardium.