Cardiac telocytes exist in the adult Xenopus tropicalis heart

Recent research has revealed that cardiac telocytes (CTs) play an important role in cardiac physiopathology and the regeneration of injured myocardium. Recently, we reported that the adult Xenopus tropicalis heart can regenerate perfectly in a nearly scar‐free manner after injury via apical resectio...

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Autores principales: Lv, Luocheng, Liao, Zhaofu, Luo, Jiali, Chen, Hongyi, Guo, Hongyan, Yang, Jifeng, Huang, Ruijin, Pu, Qin, Zhao, Hui, Yuan, Ziqiang, Feng, Shanshan, Qi, Xufeng, Cai, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028868/
https://www.ncbi.nlm.nih.gov/pubmed/31930692
http://dx.doi.org/10.1111/jcmm.14947
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author Lv, Luocheng
Liao, Zhaofu
Luo, Jiali
Chen, Hongyi
Guo, Hongyan
Yang, Jifeng
Huang, Ruijin
Pu, Qin
Zhao, Hui
Yuan, Ziqiang
Feng, Shanshan
Qi, Xufeng
Cai, Dongqing
author_facet Lv, Luocheng
Liao, Zhaofu
Luo, Jiali
Chen, Hongyi
Guo, Hongyan
Yang, Jifeng
Huang, Ruijin
Pu, Qin
Zhao, Hui
Yuan, Ziqiang
Feng, Shanshan
Qi, Xufeng
Cai, Dongqing
author_sort Lv, Luocheng
collection PubMed
description Recent research has revealed that cardiac telocytes (CTs) play an important role in cardiac physiopathology and the regeneration of injured myocardium. Recently, we reported that the adult Xenopus tropicalis heart can regenerate perfectly in a nearly scar‐free manner after injury via apical resection. However, whether telocytes exist in the X tropicalis heart and are affected in the regeneration of injured X tropicalis myocardium is still unknown. The present ultrastructural and immunofluorescent double staining results clearly showed that CTs exist in the X tropicalis myocardium. CTs in the X tropicalis myocardium were mainly twined around the surface of cardiomyocyte trabeculae and linked via nanocontacts between the ends of the telopodes, forming a three‐dimensional network. CTs might play a role in the regeneration of injured myocardium.
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spelling pubmed-70288682020-02-19 Cardiac telocytes exist in the adult Xenopus tropicalis heart Lv, Luocheng Liao, Zhaofu Luo, Jiali Chen, Hongyi Guo, Hongyan Yang, Jifeng Huang, Ruijin Pu, Qin Zhao, Hui Yuan, Ziqiang Feng, Shanshan Qi, Xufeng Cai, Dongqing J Cell Mol Med Original Articles Recent research has revealed that cardiac telocytes (CTs) play an important role in cardiac physiopathology and the regeneration of injured myocardium. Recently, we reported that the adult Xenopus tropicalis heart can regenerate perfectly in a nearly scar‐free manner after injury via apical resection. However, whether telocytes exist in the X tropicalis heart and are affected in the regeneration of injured X tropicalis myocardium is still unknown. The present ultrastructural and immunofluorescent double staining results clearly showed that CTs exist in the X tropicalis myocardium. CTs in the X tropicalis myocardium were mainly twined around the surface of cardiomyocyte trabeculae and linked via nanocontacts between the ends of the telopodes, forming a three‐dimensional network. CTs might play a role in the regeneration of injured myocardium. John Wiley and Sons Inc. 2020-01-12 2020-02 /pmc/articles/PMC7028868/ /pubmed/31930692 http://dx.doi.org/10.1111/jcmm.14947 Text en © 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Lv, Luocheng
Liao, Zhaofu
Luo, Jiali
Chen, Hongyi
Guo, Hongyan
Yang, Jifeng
Huang, Ruijin
Pu, Qin
Zhao, Hui
Yuan, Ziqiang
Feng, Shanshan
Qi, Xufeng
Cai, Dongqing
Cardiac telocytes exist in the adult Xenopus tropicalis heart
title Cardiac telocytes exist in the adult Xenopus tropicalis heart
title_full Cardiac telocytes exist in the adult Xenopus tropicalis heart
title_fullStr Cardiac telocytes exist in the adult Xenopus tropicalis heart
title_full_unstemmed Cardiac telocytes exist in the adult Xenopus tropicalis heart
title_short Cardiac telocytes exist in the adult Xenopus tropicalis heart
title_sort cardiac telocytes exist in the adult xenopus tropicalis heart
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028868/
https://www.ncbi.nlm.nih.gov/pubmed/31930692
http://dx.doi.org/10.1111/jcmm.14947
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