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Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population
The functional variants involved in alcohol metabolism, the A allele of rs1229984:A > G in ADH1B and the A allele of rs671:G > A in ALDH2, are specifically prevalent among East Asian population. They are shown to be under recent positive selection, but the reasons for the selection are unknown...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028931/ https://www.ncbi.nlm.nih.gov/pubmed/31558841 http://dx.doi.org/10.1038/s41431-019-0518-y |