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Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets
Glucagon-like peptide 1 (GLP-1) and cholecystokinin (CCK) are gut-derived peptide hormones known to play important roles in the regulation of gastrointestinal motility and secretion, appetite, and food intake. We have previously demonstrated that both GLP-1 and CCK are produced in the endocrine panc...
Autores principales: | de Souza, Arnaldo Henrique, Tang, Jiayin, Yadev, Amanjot Kaur, Saghafi, Samuel T., Kibbe, Carly R., Linnemann, Amelia K., Merrins, Matthew J., Davis, Dawn Belt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028949/ https://www.ncbi.nlm.nih.gov/pubmed/32071395 http://dx.doi.org/10.1038/s41598-020-59799-2 |
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