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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

Autophagy, a conserved cellular degradation and recycling process, can be enhanced by nutrient depletion, oxidative stress or other harmful conditions to maintain cell survival. 6-Hydroxydopamine/ascorbic acid (6-OHDA/AA) is commonly used to induce experimental Parkinson’s disease (PD) lesions by ca...

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Detalles Bibliográficos
Autores principales:	Zhuang, Xu-Xu, Wang, Sheng-Fang, Tan, Yuan, Song, Ju-Xian, Zhu, Zhou, Wang, Zi-Ying, Wu, Ming-Yue, Cai, Cui-Zan, Huang, Zhi-Jian, Tan, Jie-Qiong, Su, Huan-Xing, Li, Min, Lu, Jia-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028954/ https://www.ncbi.nlm.nih.gov/pubmed/32071296 http://dx.doi.org/10.1038/s41419-020-2322-6

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