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Nucleolar localization of the Notch4 intracellular domain underpins its regulation of the cellular response to genotoxic stressors
Cell survival is one of the many cellular processes regulated by Notch family of proteins. A comparison of human breast cancer cell lines, which differ in the levels of endogenous Notch4, implicated the protein in regulating susceptibility to apoptosis triggered by genomic damage. In agreement with...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029026/ https://www.ncbi.nlm.nih.gov/pubmed/32123583 http://dx.doi.org/10.1038/s41420-020-0242-y |