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Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding
Type IV secretion systems (T4SSs) are sophisticated nanomachines used by many bacterial pathogens to translocate protein and DNA substrates across a host cell membrane. Although T4SSs have important roles in promoting bacterial infections, little is known about the biogenesis of the apparatus and th...
Autores principales: | Park, Donghyun, Chetrit, David, Hu, Bo, Roy, Craig R., Liu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029142/ https://www.ncbi.nlm.nih.gov/pubmed/32071271 http://dx.doi.org/10.1128/mBio.03328-19 |
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