Fingolimod inhibits proliferation and epithelial–mesenchymal transition in sacral chordoma by inactivating IL-6/STAT3 signalling

Purpose: To explore the sensitivity of the immunosuppressive agent fingolimod (FTY720) in chordoma and determine whether it can serve as an appropriate alternate treatment for unresectable tumours in patients after incomplete surgery. Methods: Cell viability assays, colony formation assays and EdU a...

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Detalles Bibliográficos
Autores principales: Wang, Jiaqi, Hu, Wenhao, Du, Xiaowen, Sun, Ying, Han, Shuai, Tu, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029154/
https://www.ncbi.nlm.nih.gov/pubmed/32027356
http://dx.doi.org/10.1042/BSR20200221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029154/
https://www.ncbi.nlm.nih.gov/pubmed/32027356
http://dx.doi.org/10.1042/BSR20200221

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