Cargando…

Quantification of Alfacalcidol Tablets Dissolution Content by Chemical Derivatization and LC-MS

Application of liquid chromatography-mass spectrometry (LC-MS) in analyzing the content of alfacalcidol tablets dissolution faces big challenges due to the low amount of alfacalcidol in each tablet and the low ionization efficacy of the compound with electrospray ionization (ESI) or atmospheric-pres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yang, Chen, Xi, Yuan, Song, Liu, Wanhui, He, Lan, Zhang, Qingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029283/ https://www.ncbi.nlm.nih.gov/pubmed/32089948 http://dx.doi.org/10.1155/2020/6201656

Ejemplares similares

Quantification of Cellular Folate Species by LC-MS after Stabilization by Derivatization
por: Schittmayer, Matthias, et al.
Publicado: (2018)

In Matrix Derivatization Combined with LC-MS/MS Results in Ultrasensitive Quantification of Plasma Free Metanephrines and Catecholamines
por: van Faassen, Martijn, et al.
Publicado: (2020)

Sensitive Detection of 8-Nitroguanine in DNA by Chemical Derivatization Coupled with Online Solid-Phase Extraction LC-MS/MS
por: Hu, Chiung-Wen, et al.
Publicado: (2018)

Integrated LC-MS metabolomics with dual derivatization for quantification of FFAs in fecal samples of hepatocellular carcinoma patients
por: Zhang, Jiangang, et al.
Publicado: (2021)

Stability of sample extracts of vitamin D(3) metabolites after chemical derivatization for LC–MS/MS analysis
por: Alexandridou, Anastasia, et al.
Publicado: (2022)

Enhanced LC-ESI-MS/MS Sensitivity by Cationic Derivatization of Organophosphorus Acids
por: Shamai Yamin, Tamar, et al.
Publicado: (2023)

Monitoring diacylglycerols in biofluids by non-isotopically paired charge derivatization combined with LC-MS/MS
por: Liu, Yang-Dan, et al.
Publicado: (2022)

A novel LC-MS/MS method combined with derivatization for simultaneous quantification of vitamin D metabolites in human serum with diabetes as well as hyperlipidemia
por: Wang, Xiaodi, et al.
Publicado: (2023)

Targeted LC–MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA
por: Eggink, Mark, et al.
Publicado: (2010)

Metabolomics of Clinical Poisoning by Aconitum Alkaloids Using Derivatization LC-MS
por: Zhang, Yida, et al.
Publicado: (2019)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Rapid Detection of Estrogens in Cosmetics by Chemical Derivatization and Paper-Spray Ionization Mass-Spectrometry
por: Song, Dongning, et al.
Publicado: (2023)

Development and Verification of a Precolumn Derivatization LC-MS/MS Method for the Pharmacokinetic Study of Houttuynine of Houttuynia Essential Oil
por: Liu, Yuanyuan, et al.
Publicado: (2021)

Comparing derivatization reagents for quantitative LC–MS/MS analysis of a variety of vitamin D metabolites
por: Alexandridou, Anastasia, et al.
Publicado: (2023)

Derivatization of Methylglyoxal for LC-ESI-MS Analysis—Stability and Relative Sensitivity of Different Derivatives
por: Fritzsche, Stefan, et al.
Publicado: (2018)

Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study
por: Bhadoriya, Abhaysingh, et al.
Publicado: (2018)

MTBSTFA derivatization-LC-MS/MS approach for the quantitative analysis of endogenous nucleotides in human colorectal carcinoma cells
por: Zhang, Huixia, et al.
Publicado: (2022)

Chemical Profiling of Kaliziri Injection and Quantification of Six Caffeoyl Quinic Acids in Beagle Plasma by LC-MS/MS
por: Liu, Changhua, et al.
Publicado: (2022)

2-Hydrazinoquinoline as a Derivatization Agent for LC-MS-Based Metabolomic Investigation of Diabetic Ketoacidosis
por: Lu, Yuwei, et al.
Publicado: (2013)

Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
por: Gamon, Luke F., et al.
Publicado: (2020)

Detection of Podocin in Human Urine Sediment Samples by Charge Derivatization and LC-MS-MRM Method
por: Bąchor, Remigiusz, et al.
Publicado: (2020)

A Practical Method for Amino Acid Analysis by LC-MS Using Precolumn Derivatization with Urea
por: Zhao, Runjin, et al.
Publicado: (2023)

Determination of Dodecanol and Short-Chained Ethoxylated Dodecanols by LC–MS/MS (with Electrospray Ionization) After Their Derivatization (with Phenyl Isocyanate)
por: Zembrzuska, Joanna
Publicado: (2017)

ODP179 Development of Derivatization-free ID-LC/MS/MS Method for Simultaneous Measurement of Human Serum Monosaccharides
por: Tse, Chui, et al.
Publicado: (2022)

Pharmacovigilance of Herb-Drug Interactions: A Pharmacokinetic Study on the Combined Administration of Tripterygium Glycosides Tablets and Leflunomide Tablets in Rats by LC-MS/MS
por: Boucetta, Hamza, et al.
Publicado: (2022)

Dissolution and uniformity of content of tablets developed with extract of Ximenia americana L.
por: Santana, Cleildo P., et al.
Publicado: (2018)

Determination of ergocalciferol in human plasma after Diels-Alder derivatization by LC–MS/MS and its application to a bioequivalence study
por: Contractor, Pritesh, et al.
Publicado: (2017)

Trimethylacetic Anhydride–Based Derivatization Facilitates Quantification of Histone Marks at the MS1 Level
por: Kuchaříková, Hana, et al.
Publicado: (2021)

Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS
por: Atrih, Abdelmadjid, et al.
Publicado: (2009)

2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites
por: Alexandridou, Anastasia, et al.
Publicado: (2023)

Early bioprosthetic valve calcification with alfacalcidol supplementation
por: Takano, Tamaki, et al.
Publicado: (2013)

Ion-Pairing Chromatography and Amine Derivatization Provide Complementary Approaches for the Targeted LC-MS Analysis of the Polar Metabolome
por: Sagi-Kiss, Virag, et al.
Publicado: (2022)

Liquid Chromatography-Mass Spectrometry (LC-MS) Derivatization-Based Methods for the Determination of Fatty Acids in Biological Samples
por: Mantzourani, Christiana, et al.
Publicado: (2022)

Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag(+)CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack
por: Cha, Eunju, et al.
Publicado: (2016)

Pipelines and Systems for Threshold-Avoiding Quantification of LC–MS/MS Data
por: Sánchez Brotons, Alejandro, et al.
Publicado: (2021)

Estimation of measurement uncertainty for the quantification of protein by ID-LC–MS/MS
por: Beasley-Green, Ashley, et al.
Publicado: (2023)

Pharmacokinetics and Bioequivalence Study of Hydroxychloroquine Sulfate Tablets in Chinese Healthy Volunteers by LC–MS/MS
por: Fan, Hong-wei, et al.
Publicado: (2015)

Monolithic LC method applied to fesoterodine fumarate low dose extended-release tablets: Dissolution and release kinetics
por: Sangoi, Maximiliano S., et al.
Publicado: (2015)

Ultrasensitive Quantification of Multiple Estrogens in Songbird Blood and Microdissected Brain by LC-MS/MS
por: Jalabert, Cecilia, et al.
Publicado: (2022)

Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and (15)N-labeling
por: Mallia, Vittoria, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fehsptkaa90kr82meceda15hkp