Cargando…

Misaponin B Induces G2/M Arrest, Cytokinesis Failure and Impairs Autophagy

Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Won, Gunho, Jung, Ji Hoon, Sohn, Eun Jung, Park, Ji Eon, Kim, Hyungjin, Lee, Hyo-Jung, Shim, Bum Sang, Kim, Sung-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029305/ https://www.ncbi.nlm.nih.gov/pubmed/32090100 http://dx.doi.org/10.1155/2020/5925094

Ejemplares similares

Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
por: Cho, Ah-Reum, et al.
Publicado: (2021)

Activation of JNK and IRE1 is critically involved in tanshinone I-induced p62 dependent autophagy in malignant pleural mesothelioma cells: implication of p62 UBA domain
por: Lee, Jihyun, et al.
Publicado: (2017)

Inhibition of Wnt3a/FOXM1/β-Catenin Axis and Activation of GSK3β and Caspases are Critically Involved in Apoptotic Effect of Moracin D in Breast Cancers
por: Hwang, Sung Min, et al.
Publicado: (2018)

Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation
por: Kim, Karam, et al.
Publicado: (2018)

The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling
por: Kim, Hyungjin, et al.
Publicado: (2022)

Upregulation of miRNA3195 and miRNA374b Mediates the Anti-Angiogenic Properties of Melatonin in Hypoxic PC-3 Prostate Cancer Cells
por: Sohn, Eun Jung, et al.
Publicado: (2015)

miR193a-5p Mediated ZNF746 and c-Myc Signaling Axis Is Critically Involved in Morusin Induced Apoptosis in Colorectal Cancer Cells
por: Park, Woon-Yi, et al.
Publicado: (2021)

The Apoptotic and Anti-Warburg Effects of Brassinin in PC-3 Cells via Reactive Oxygen Species Production and the Inhibition of the c-Myc, SIRT1, and β-Catenin Signaling Axis
por: Kwon, Hyeon Hee, et al.
Publicado: (2023)

Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H(2)AX, CHK2 and p53
por: Kim, Ji-Hyun, et al.
Publicado: (2022)

Farnesiferol C Induces Apoptosis in Chronic Myelogenous Leukemia Cells as an Imatinib Sensitizer via Caspase Activation and HDAC (Histone Deacetylase) Inactivation
por: Jung, Ji Hoon, et al.
Publicado: (2019)

Antitumor Effect of Pyrogallol via miR-134 Mediated S Phase Arrest and Inhibition of PI3K/AKT/Skp2/cMyc Signaling in Hepatocellular Carcinoma
por: Ahn, Hyojin, et al.
Publicado: (2019)

Ethanol Extract of Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation of BDNF, P-CREB and Inhibition of Acetylcholinesterase
por: Lee, Jung Eun, et al.
Publicado: (2018)

Lee, J.E. et al. Ethanol Extract of Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation of BDNF, P-CREB and Inhibition of Acetylcholinesterase
por: Lee, Jung Eun, et al.
Publicado: (2018)

NEDD9 Inhibition by miR-25-5p Activation Is Critically Involved in Co-Treatment of Melatonin- and Pterostilbene-Induced Apoptosis in Colorectal Cancer Cells
por: Jung, Ji Hoon, et al.
Publicado: (2019)

Recent Advances in Nanotechnology with Nano-Phytochemicals: Molecular Mechanisms and Clinical Implications in Cancer Progression
por: Kim, Bonglee, et al.
Publicado: (2021)

Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell
por: Sohn, Eun Jung, et al.
Publicado: (2016)

Implicit Regularization for Reconstructing 3D Building Rooftop Models Using Airborne LiDAR Data
por: Jung, Jaewook, et al.
Publicado: (2017)

Inhibition of STAT3/PD-L1 and Activation of miR193a-5p Are Critically Involved in Apoptotic Effect of Compound K in Prostate Cancer Cells
por: Lee, Jae-Hee, et al.
Publicado: (2021)

UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11
por: Kim, Ju-Ha, et al.
Publicado: (2021)

Activation of AMP-Activated Protein Kinase α and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells
por: Cho, Sung-Yun, et al.
Publicado: (2013)

Corrigendum to “Activation of AMP-Activated Protein Kinase and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells”
por: Cho, Sung-Yun, et al.
Publicado: (2020)

Postoperative Ureteral Leak Treated Using a Silicone-Covered Nitinol Stent
por: Park, Hyo Jung, et al.
Publicado: (2015)

Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway
por: Lee, Seung-On, et al.
Publicado: (2021)

Upregulation of microRNA135a-3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis
por: Shin, Eun Ah, et al.
Publicado: (2014)

Correction: Upregulation of microRNA135a-3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis
por: Shin, Eun Ah, et al.
Publicado: (2018)

Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells
por: Cho, Sung-Yun, et al.
Publicado: (2013)

Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells
por: Jang, Jinsil, et al.
Publicado: (2013)

Neuronal autophagy and neurodegenerative diseases
por: Son, Jin H., et al.
Publicado: (2012)

Impaired Sacculocollic Reflex in Lateral Medullary Infarction
por: Kim, Seonhye, et al.
Publicado: (2011)

OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin
por: Koh, Young Ik, et al.
Publicado: (2022)

Melatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells
por: Jung, Ji Hoon, et al.
Publicado: (2013)

Erratum to “Melatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells”
por: Jung, Ji Hoon, et al.
Publicado: (2019)

Thrombocythemia 1 With THPO Variant (c.13+1G>A) Diagnosed Using Targeted Exome Sequencing: First Case in Korea
por: Jung, Nani, et al.
Publicado: (2020)

Role of Endoscopic Procedures in the Diagnosis of IgG4-Related Pancreatobiliary Disease
por: Jung, Ye-Ji, et al.
Publicado: (2021)

Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia
por: Rogne, Marie, et al.
Publicado: (2018)

Triggering p53 after cytokinesis failure
por: Stukenberg, P. Todd
Publicado: (2004)

Inhibitory effect of ethanol extract of Ocimum sanctum on osteopontin mediated metastasis of NCI-H460 non-small cell lung cancer cells
por: Kwak, Tae-kyung, et al.
Publicado: (2014)

Licochalcone H Induces Cell Cycle Arrest and Apoptosis in Human Skin Cancer Cells by Modulating JAK2/STAT3 Signaling
por: Park, Kyung-Ho, et al.
Publicado: (2022)

Stimulation of Toll-Like Receptor 3 Diminishes Intracellular Growth of Salmonella Typhimurium by Enhancing Autophagy in Murine Macrophages
por: Lee, Hyo-Ji, et al.
Publicado: (2021)

Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells
por: Han, Jonghyun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lpo15o8n1a7tehobkq92sav57b