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Histone deacetylase inhibitor pre-treatment enhances the efficacy of DNA-interacting chemotherapeutic drugs in gastric cancer
BACKGROUND: The prognosis of gastric cancer continues to remain poor, and epigenetic drugs like histone deacetylase inhibitors (HDACi) have been envisaged as potential therapeutic agents. Nevertheless, clinical trials are facing issues with toxicity and efficacy against solid tumors, which may be pa...
Autores principales: | Amnekar, Ramchandra Vigay, Khan, Shafqat Ali, Rashid, Mudasir, Khade, Bharat, Thorat, Rahul, Gera, Poonam, Shrikhande, Shailesh V, Smoot, Duane T, Ashktorab, Hassan, Gupta, Sanjay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029347/ https://www.ncbi.nlm.nih.gov/pubmed/32103870 http://dx.doi.org/10.3748/wjg.v26.i6.598 |
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