Cargando…

Allergic reactions to genus Morus plants: a review

Mulberry is a plant belonging to the family Moraceae, and genus Morus. Allergic sensitization to mulberries has been reported as both food allergy or respiratory allergy, and cross-reactivity between mulberries and other pollens or fruits was described. Clinically, in the articles reporting mulberry...

Descripción completa

Detalles Bibliográficos
Autores principales: Papia, F., Incorvaia, C., Genovese, L., Gangemi, S., Minciullo, P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029495/
https://www.ncbi.nlm.nih.gov/pubmed/32099533
http://dx.doi.org/10.1186/s12948-020-00116-7
_version_ 1783499179638652928
author Papia, F.
Incorvaia, C.
Genovese, L.
Gangemi, S.
Minciullo, P. L.
author_facet Papia, F.
Incorvaia, C.
Genovese, L.
Gangemi, S.
Minciullo, P. L.
author_sort Papia, F.
collection PubMed
description Mulberry is a plant belonging to the family Moraceae, and genus Morus. Allergic sensitization to mulberries has been reported as both food allergy or respiratory allergy, and cross-reactivity between mulberries and other pollens or fruits was described. Clinically, in the articles reporting mulberry allergy, the reactions included respiratory allergy, airborne contact urticaria, anaphylaxis, oral allergy syndrome, and food induced urticaria. As far as cross-reactivity is concerned, the allergens identified thus far in mulberries include pathogenesis-related (PR)10 proteins, with sequence identity to Bet v 1 from birch, lipid transfer (LTP)1 proteins with identity with LTPs from Rosaceae family plants, panallergens groups, and also ubiquitin-like protein and cystatin-like protein. The two latter proteins account for cross-reactions with Parietaria judaica and Olea europaea. Such large cross-reactivity warrants to pay particular attention to the risk of systemic reactions to foods, particularly in subjects sensitized to birch, parietaria or olive pollens. In fact, the increasing use of mulberry as a food product, which is encouraged by its remarkable antioxidant power, expose sensitized patients to possible reactions after ingesting foods, dietary supplements or nutraceuticals containing mulberry. Mulberry allergenicity can vary according to the processing methods used since some allergens are thermostable and other loss their reactivity during heating.
format Online
Article
Text
id pubmed-7029495
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-70294952020-02-25 Allergic reactions to genus Morus plants: a review Papia, F. Incorvaia, C. Genovese, L. Gangemi, S. Minciullo, P. L. Clin Mol Allergy Review Mulberry is a plant belonging to the family Moraceae, and genus Morus. Allergic sensitization to mulberries has been reported as both food allergy or respiratory allergy, and cross-reactivity between mulberries and other pollens or fruits was described. Clinically, in the articles reporting mulberry allergy, the reactions included respiratory allergy, airborne contact urticaria, anaphylaxis, oral allergy syndrome, and food induced urticaria. As far as cross-reactivity is concerned, the allergens identified thus far in mulberries include pathogenesis-related (PR)10 proteins, with sequence identity to Bet v 1 from birch, lipid transfer (LTP)1 proteins with identity with LTPs from Rosaceae family plants, panallergens groups, and also ubiquitin-like protein and cystatin-like protein. The two latter proteins account for cross-reactions with Parietaria judaica and Olea europaea. Such large cross-reactivity warrants to pay particular attention to the risk of systemic reactions to foods, particularly in subjects sensitized to birch, parietaria or olive pollens. In fact, the increasing use of mulberry as a food product, which is encouraged by its remarkable antioxidant power, expose sensitized patients to possible reactions after ingesting foods, dietary supplements or nutraceuticals containing mulberry. Mulberry allergenicity can vary according to the processing methods used since some allergens are thermostable and other loss their reactivity during heating. BioMed Central 2020-02-19 /pmc/articles/PMC7029495/ /pubmed/32099533 http://dx.doi.org/10.1186/s12948-020-00116-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Papia, F.
Incorvaia, C.
Genovese, L.
Gangemi, S.
Minciullo, P. L.
Allergic reactions to genus Morus plants: a review
title Allergic reactions to genus Morus plants: a review
title_full Allergic reactions to genus Morus plants: a review
title_fullStr Allergic reactions to genus Morus plants: a review
title_full_unstemmed Allergic reactions to genus Morus plants: a review
title_short Allergic reactions to genus Morus plants: a review
title_sort allergic reactions to genus morus plants: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029495/
https://www.ncbi.nlm.nih.gov/pubmed/32099533
http://dx.doi.org/10.1186/s12948-020-00116-7
work_keys_str_mv AT papiaf allergicreactionstogenusmorusplantsareview
AT incorvaiac allergicreactionstogenusmorusplantsareview
AT genovesel allergicreactionstogenusmorusplantsareview
AT gangemis allergicreactionstogenusmorusplantsareview
AT minciullopl allergicreactionstogenusmorusplantsareview