Transforming growth factor β1 accelerates and enhances in vitro red blood cell formation from hematopoietic stem cells by stimulating mitophagy

BACKGROUND: Generation of red blood cells (RBCs) from hematopoietic stem cells (HSCs) in vitro takes about 21 days, making it unaffordable for clinical applications. Acceleration of the in vitro erythropoiesis process by using small molecules could eventually make the large-scale production of these...

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Detalles Bibliográficos
Autores principales: Kuhikar, Rutuja, Khan, Nikhat, Philip, Joseph, Melinkeri, Sameer, Kale, Vaijayanti, Limaye, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029523/
https://www.ncbi.nlm.nih.gov/pubmed/32075694
http://dx.doi.org/10.1186/s13287-020-01603-z

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