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Influenza vaccination in early Alzheimer’s disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disorder strongly correlated with a dysfunctional immune system. Our previous results demonstrated that inactivated influenza vaccine (IIV) facilitates hippocampal neurogenesis and blocks lipopolysaccharide (LPS)-induced cognitive impairmen...

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Detalles Bibliográficos
Autores principales:	Yang, Yunjie, He, Zitian, Xing, Zhiwei, Zuo, Zejie, Yuan, Lifang, Wu, Yingying, Jiang, Mei, Qi, Fangfang, Yao, Zhibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029575/ https://www.ncbi.nlm.nih.gov/pubmed/32075657 http://dx.doi.org/10.1186/s12974-020-01741-4

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