TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic and ultimately fatal disease characterized by a progressive decline in lung function. Fibrotic diseases, such as IPF, are characterized by uncontrolled activation of fibroblasts. Since the microenvironment is known to affect cell behavior,...

Descripción completa

Detalles Bibliográficos
Autores principales: Epstein Shochet, Gali, Brook, Elizabetha, Bardenstein-Wald, Becky, Shitrit, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029598/
https://www.ncbi.nlm.nih.gov/pubmed/32070329
http://dx.doi.org/10.1186/s12931-020-1319-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029598/
https://www.ncbi.nlm.nih.gov/pubmed/32070329
http://dx.doi.org/10.1186/s12931-020-1319-0

Ejemplares similares