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CD4(+) T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4(+) Cells
T follicular helper (Tfh) cells are fundamental for B cell selection and antibody maturation in germinal centers. Circulating Tfh (cTfh) cells constitute a minor proportion of the CD4(+) T cells in peripheral blood, but their clonotypic relationship to Tfh populations resident in lymph nodes and the...
Autores principales: | Brenna, Elena, Davydov, Alexey N., Ladell, Kristin, McLaren, James E., Bonaiuti, Paolo, Metsger, Maria, Ramsden, James D., Gilbert, Sarah C., Lambe, Teresa, Price, David A., Campion, Suzanne L., Chudakov, Dmitriy M., Borrow, Persephone, McMichael, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029615/ https://www.ncbi.nlm.nih.gov/pubmed/31914381 http://dx.doi.org/10.1016/j.celrep.2019.12.016 |
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