Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)

In article number https://doi.org/10.1002/advs.201902621, Tamás A. Martinek and co‐workers develop a pentapeptidic tag, which reads the glycan code of ganglioside GM1 and triggers lipid raft‐mediated endocytosis, avoiding lysosomal entrapment. This carrier molecule can deliver macromolecular cargoes...

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Detalles Bibliográficos
Autores principales: Imre, Norbert, Hetényi, Anasztázia, Szabó, Enikő, Bodnár, Brigitta, Szkalisity, Abel, Gróf, Ilona, Bocsik, Alexandra, Deli, Mária A., Horvath, Peter, Czibula, Ágnes, Monostori, Éva, Martinek, Tamás A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029659/
http://dx.doi.org/10.1002/advs.202070019
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author Imre, Norbert
Hetényi, Anasztázia
Szabó, Enikő
Bodnár, Brigitta
Szkalisity, Abel
Gróf, Ilona
Bocsik, Alexandra
Deli, Mária A.
Horvath, Peter
Czibula, Ágnes
Monostori, Éva
Martinek, Tamás A.
author_facet Imre, Norbert
Hetényi, Anasztázia
Szabó, Enikő
Bodnár, Brigitta
Szkalisity, Abel
Gróf, Ilona
Bocsik, Alexandra
Deli, Mária A.
Horvath, Peter
Czibula, Ágnes
Monostori, Éva
Martinek, Tamás A.
author_sort Imre, Norbert
collection PubMed
description In article number https://doi.org/10.1002/advs.201902621, Tamás A. Martinek and co‐workers develop a pentapeptidic tag, which reads the glycan code of ganglioside GM1 and triggers lipid raft‐mediated endocytosis, avoiding lysosomal entrapment. This carrier molecule can deliver macromolecular cargoes (e.g., IgG complexes) into live cells with the possibility to escape to the cytosol. [Image: see text]
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spelling pubmed-70296592020-02-25 Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020) Imre, Norbert Hetényi, Anasztázia Szabó, Enikő Bodnár, Brigitta Szkalisity, Abel Gróf, Ilona Bocsik, Alexandra Deli, Mária A. Horvath, Peter Czibula, Ágnes Monostori, Éva Martinek, Tamás A. Adv Sci (Weinh) Inside Front Cover In article number https://doi.org/10.1002/advs.201902621, Tamás A. Martinek and co‐workers develop a pentapeptidic tag, which reads the glycan code of ganglioside GM1 and triggers lipid raft‐mediated endocytosis, avoiding lysosomal entrapment. This carrier molecule can deliver macromolecular cargoes (e.g., IgG complexes) into live cells with the possibility to escape to the cytosol. [Image: see text] John Wiley and Sons Inc. 2020-02-19 /pmc/articles/PMC7029659/ http://dx.doi.org/10.1002/advs.202070019 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Front Cover
Imre, Norbert
Hetényi, Anasztázia
Szabó, Enikő
Bodnár, Brigitta
Szkalisity, Abel
Gróf, Ilona
Bocsik, Alexandra
Deli, Mária A.
Horvath, Peter
Czibula, Ágnes
Monostori, Éva
Martinek, Tamás A.
Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title_full Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title_fullStr Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title_full_unstemmed Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title_short Cell Delivery: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag (Adv. Sci. 4/2020)
title_sort cell delivery: routing nanomolar protein cargoes to lipid raft‐mediated/caveolar endocytosis through a ganglioside gm1‐specific recognition tag (adv. sci. 4/2020)
topic Inside Front Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029659/
http://dx.doi.org/10.1002/advs.202070019
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