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Can oral health and oral‐derived biospecimens predict progression of dementia?

Growing evidence indicates that oral health and brain health are interconnected. Declining cognition and dementia coincide with lack of self‐preservation, including oral hygiene. The oral microbiota plays an important role in maintaining oral health. Emerging evidence suggests a link between oral dy...

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Detalles Bibliográficos
Autores principales: Orr, Miranda E., Reveles, Kelly R., Yeh, Chih‐Ko, Young, Eric H., Han, Xianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031023/
https://www.ncbi.nlm.nih.gov/pubmed/31541581
http://dx.doi.org/10.1111/odi.13201
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author Orr, Miranda E.
Reveles, Kelly R.
Yeh, Chih‐Ko
Young, Eric H.
Han, Xianlin
author_facet Orr, Miranda E.
Reveles, Kelly R.
Yeh, Chih‐Ko
Young, Eric H.
Han, Xianlin
author_sort Orr, Miranda E.
collection PubMed
description Growing evidence indicates that oral health and brain health are interconnected. Declining cognition and dementia coincide with lack of self‐preservation, including oral hygiene. The oral microbiota plays an important role in maintaining oral health. Emerging evidence suggests a link between oral dysbiosis and cognitive decline in patients with Alzheimer's disease. This review showcases the recent advances connecting oral health and cognitive function during aging and the potential utility of oral‐derived biospecimens to inform on brain health. Collectively, experimental findings indicate that the connection between oral health and cognition cannot be underestimated; moreover, oral biospecimens are abundant and readily obtainable without invasive procedures, which may help inform on cognitive health.
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spelling pubmed-70310232020-03-16 Can oral health and oral‐derived biospecimens predict progression of dementia? Orr, Miranda E. Reveles, Kelly R. Yeh, Chih‐Ko Young, Eric H. Han, Xianlin Oral Dis Invited Concise Review Growing evidence indicates that oral health and brain health are interconnected. Declining cognition and dementia coincide with lack of self‐preservation, including oral hygiene. The oral microbiota plays an important role in maintaining oral health. Emerging evidence suggests a link between oral dysbiosis and cognitive decline in patients with Alzheimer's disease. This review showcases the recent advances connecting oral health and cognitive function during aging and the potential utility of oral‐derived biospecimens to inform on brain health. Collectively, experimental findings indicate that the connection between oral health and cognition cannot be underestimated; moreover, oral biospecimens are abundant and readily obtainable without invasive procedures, which may help inform on cognitive health. John Wiley and Sons Inc. 2020-01-06 2020-03 /pmc/articles/PMC7031023/ /pubmed/31541581 http://dx.doi.org/10.1111/odi.13201 Text en © 2019 The Authors. Oral Diseases published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Concise Review
Orr, Miranda E.
Reveles, Kelly R.
Yeh, Chih‐Ko
Young, Eric H.
Han, Xianlin
Can oral health and oral‐derived biospecimens predict progression of dementia?
title Can oral health and oral‐derived biospecimens predict progression of dementia?
title_full Can oral health and oral‐derived biospecimens predict progression of dementia?
title_fullStr Can oral health and oral‐derived biospecimens predict progression of dementia?
title_full_unstemmed Can oral health and oral‐derived biospecimens predict progression of dementia?
title_short Can oral health and oral‐derived biospecimens predict progression of dementia?
title_sort can oral health and oral‐derived biospecimens predict progression of dementia?
topic Invited Concise Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031023/
https://www.ncbi.nlm.nih.gov/pubmed/31541581
http://dx.doi.org/10.1111/odi.13201
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