Cargando…

Epiglottic granular cell tumour: a case report and literature review

Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oeso...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouayyad, Sarah, Ong, Jen, Bouayyad, Houda, Woodun, Heerani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031075/
https://www.ncbi.nlm.nih.gov/pubmed/32099640
http://dx.doi.org/10.1093/jscr/rjaa009
_version_ 1783499296513982464
author Bouayyad, Sarah
Ong, Jen
Bouayyad, Houda
Woodun, Heerani
author_facet Bouayyad, Sarah
Ong, Jen
Bouayyad, Houda
Woodun, Heerani
author_sort Bouayyad, Sarah
collection PubMed
description Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.
format Online
Article
Text
id pubmed-7031075
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-70310752020-02-25 Epiglottic granular cell tumour: a case report and literature review Bouayyad, Sarah Ong, Jen Bouayyad, Houda Woodun, Heerani J Surg Case Rep Case Report Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence. Oxford University Press 2020-02-19 /pmc/articles/PMC7031075/ /pubmed/32099640 http://dx.doi.org/10.1093/jscr/rjaa009 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Bouayyad, Sarah
Ong, Jen
Bouayyad, Houda
Woodun, Heerani
Epiglottic granular cell tumour: a case report and literature review
title Epiglottic granular cell tumour: a case report and literature review
title_full Epiglottic granular cell tumour: a case report and literature review
title_fullStr Epiglottic granular cell tumour: a case report and literature review
title_full_unstemmed Epiglottic granular cell tumour: a case report and literature review
title_short Epiglottic granular cell tumour: a case report and literature review
title_sort epiglottic granular cell tumour: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031075/
https://www.ncbi.nlm.nih.gov/pubmed/32099640
http://dx.doi.org/10.1093/jscr/rjaa009
work_keys_str_mv AT bouayyadsarah epiglotticgranularcelltumouracasereportandliteraturereview
AT ongjen epiglotticgranularcelltumouracasereportandliteraturereview
AT bouayyadhouda epiglotticgranularcelltumouracasereportandliteraturereview
AT woodunheerani epiglotticgranularcelltumouracasereportandliteraturereview