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Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice
Mice are among the most widely used translational models of cardiovascular aging and offer a method to quickly assess lifespan changes in a controlled environment. The standard laboratory temperature (20–22 °C), however, imposes a cold stress on mice that causes an increase in sympathetic nervous sy...
Autores principales: | Axsom, Jessie E., Nanavati, Alay P., Rutishauser, Carolyn A., Bonin, Janet E., Moen, Jack M., Lakatta, Edward G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031176/ https://www.ncbi.nlm.nih.gov/pubmed/31776883 http://dx.doi.org/10.1007/s11357-019-00126-7 |
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