Cargando…

A High Throughput Approach to Reconstruct Partial-Body and Neutron Radiation Exposures on an Individual Basis

Biodosimetry-based individualized reconstruction of complex irradiation scenarios (partial-body shielding and/or neutron + photon mixtures) can improve treatment decisions after mass-casualty radiation-related incidents. We used a high-throughput micronucleus assay with automated scanning and imagin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shuryak, Igor, Turner, Helen C., Perrier, Jay R., Cunha, Lydia, Canadell, Monica Pujol, Durrani, Mohammad H., Harken, Andrew, Bertucci, Antonella, Taveras, Maria, Garty, Guy, Brenner, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031285/ https://www.ncbi.nlm.nih.gov/pubmed/32076014 http://dx.doi.org/10.1038/s41598-020-59695-9

Ejemplares similares

Machine learning methodology for high throughput personalized neutron dose reconstruction in mixed neutron + photon exposures
por: Shuryak, Igor, et al.
Publicado: (2021)

Cytogenetically-based biodosimetry after high doses of radiation
por: Pujol-Canadell, Monica, et al.
Publicado: (2020)

Development of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage
por: Wang, Qi, et al.
Publicado: (2020)

Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype
por: Laiakis, Evagelia C., et al.
Publicado: (2019)

Machine learning approach for quantitative biodosimetry of partial-body or total-body radiation exposures by combining radiation-responsive biomarkers
por: Shuryak, Igor, et al.
Publicado: (2023)

Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model
por: Lee, Younghyun, et al.
Publicado: (2018)

Biomarker integration for improved biodosimetry of mixed neutron + photon exposures
por: Shuryak, Igor, et al.
Publicado: (2023)

Identification of differentially expressed genes and pathways in mice exposed to mixed field neutron/photon radiation
por: Broustas, Constantinos G., et al.
Publicado: (2018)

High Throughput Measurement of γH2AX DSB Repair Kinetics in a Healthy Human Population
por: Sharma, Preety M., et al.
Publicado: (2015)

Correction: High Throughput Measurement of γH2AX DSB Repair Kinetics in a Healthy Human Population
por: Sharma, Preety M., et al.
Publicado: (2015)

Comparison of gene expression response to neutron and x-ray irradiation using mouse blood
por: Broustas, Constantinos G., et al.
Publicado: (2017)

A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays
por: Shuryak, Igor, et al.
Publicado: (2022)

Discordant gene responses to radiation in humans and mice and the role of hematopoietically humanized mice in the search for radiation biomarkers
por: Ghandhi, Shanaz A., et al.
Publicado: (2019)

Radiation-Induced Carcinogenesis: Mechanistically Based Differences between Gamma-Rays and Neutrons, and Interactions with DMBA
por: Shuryak, Igor, et al.
Publicado: (2011)

Development of a high-throughput γ-H2AX assay based on imaging flow cytometry
por: Lee, Younghyun, et al.
Publicado: (2019)

The use of a centrifuge-free RABiT-II system for high-throughput micronucleus analysis
por: Repin, Mikhail, et al.
Publicado: (2019)

Ultra-high dose rate FLASH irradiator at the radiological research accelerator facility
por: Garty, Guy, et al.
Publicado: (2022)

Cross-platform validation of a mouse blood gene signature for quantitative reconstruction of radiation dose
por: Ghandhi, Shanaz A., et al.
Publicado: (2022)

Quantitative modeling of multigenerational effects of chronic ionizing radiation using targeted and nontargeted effects
por: Shuryak, Igor, et al.
Publicado: (2021)

In Reply to Welsh et al.
por: Shuryak, Igor, et al.
Publicado: (2021)

Quantitative modeling of carcinogenesis induced by single beams or mixtures of space radiations using targeted and non-targeted effects
por: Shuryak, Igor, et al.
Publicado: (2021)

Lung Cancer and Heart Disease Risks Associated With Low-Dose Pulmonary Radiotherapy to COVID-19 Patients With Different Background Risks
por: Shuryak, Igor, et al.
Publicado: (2021)

Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses
por: Buonanno, Manuela, et al.
Publicado: (2020)

Author Correction: Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses
por: Buonanno, Manuela, et al.
Publicado: (2021)

The basis and advances in clinical application of boron neutron capture therapy
por: He, Huifang, et al.
Publicado: (2021)

Searching for the Molecular Basis of Partial Deafness
por: Oziębło, Dominika, et al.
Publicado: (2022)

Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques
por: Ghandhi, Shanaz A., et al.
Publicado: (2023)

Ocular and Facial Far‐UVC Doses from Ceiling‐Mounted 222 nm Far‐UVC Fixtures
por: Duncan, Michael A., et al.
Publicado: (2022)

Mechanistic Modeling of Dose and Dose Rate Dependences of Radiation-Induced DNA Double Strand Break Rejoining Kinetics in Saccharomyces cerevisiae
por: Shuryak, Igor
Publicado: (2016)

Advantages of Synthetic Noise and Machine Learning for Analyzing Radioecological Data Sets
por: Shuryak, Igor
Publicado: (2017)

Quantitative modeling of responses to chronic ionizing radiation exposure using targeted and non-targeted effects
por: Shuryak, Igor
Publicado: (2017)

Quantitative modeling of radioactive cesium concentrations in large omnivorous mammals after the Fukushima nuclear power plant accident
por: Shuryak, Igor
Publicado: (2021)

Potential Reduction of Contralateral Second Breast-Cancer Risks by Prophylactic Mammary Irradiation: Validation in a Breast-Cancer-Prone Mouse Model
por: Shuryak, Igor, et al.
Publicado: (2013)

Kinetic basis of partial agonism at NMDA receptors
por: Kussius, Cassandra L, et al.
Publicado: (2009)

VADER: a variable dose-rate external (137)Cs irradiator for internal emitter and low dose rate studies
por: Garty, Guy, et al.
Publicado: (2020)

A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: Approach
por: Shuryak, Igor, et al.
Publicado: (2009)

A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation
por: Shuryak, Igor, et al.
Publicado: (2009)

Erratum to: A new view of radiation-induced cancer: integrating short- and long-term processes. Parts I and II
por: Shuryak, Igor, et al.
Publicado: (2011)

Theoretical basis and mathematical modeling of the thermal neutron converters based on gadolinium foils
por: Abdushukurov, Djamshed A
Publicado: (2018)

The Reliability and Stability Convertor of High Temperature Neutron Target on Basis of Graphite Composites
por: Zhmurikov, E I, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_c6e5qk2cvpe5uck8f56vetdu0a