A High-Throughput Small Molecule Screen Identifies Ouabain as Synergistic with miR-34a in Killing Lung Cancer Cells

MicroRNA-34 (miR-34) is one of the major families of tumor suppressor miRNAs often lost in cancers. Delivery of miR-34a mimics to affected tumors as a therapeutic strategy has been tried in pre-clinical studies and in a phase I clinical trial. One approach to increase efficacy and reduce toxicity is...

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Detalles Bibliográficos
Autores principales: Rupaimoole, Rajesha, Yoon, Bohyung, Zhang, Wen Cai, Adams, Brian D., Slack, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031322/
https://www.ncbi.nlm.nih.gov/pubmed/32062455
http://dx.doi.org/10.1016/j.isci.2020.100878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031322/
https://www.ncbi.nlm.nih.gov/pubmed/32062455
http://dx.doi.org/10.1016/j.isci.2020.100878

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