Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

Antigenic variation, the capacity to produce a range of variable antigens, is a well-described strategy of Plasmodium and other parasites to evade host immunity. Here, we show that gene amplification is an additional evasion mechanism used by Plasmodium vivax to escape humoral immunity targeting PvD...

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Detalles Bibliográficos
Autores principales: Popovici, Jean, Roesch, Camille, Carias, Lenore L., Khim, Nimol, Kim, Saorin, Vantaux, Amelie, Mueller, Ivo, Chitnis, Chetan E., King, Christopher L., Witkowski, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031336/
https://www.ncbi.nlm.nih.gov/pubmed/32075983
http://dx.doi.org/10.1038/s41467-020-14574-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031336/
https://www.ncbi.nlm.nih.gov/pubmed/32075983
http://dx.doi.org/10.1038/s41467-020-14574-9

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