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Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors
Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from benign plexiform neurofibromas in neurofibromatosis type 1 (NF1) patients. MPNSTs metastasize easily, are therapy resistant and are frequently fatal. The molecular changes underl...
Autores principales: | Amirnasr, Azadeh, Verdijk, Robert M., van Kuijk, Patricia F., Kartal, Pinar, Vriends, Anne L. M., French, Pim J., van Royen, Martin E., Taal, Walter, Sleijfer, Stefan, Wiemer, Erik A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031337/ https://www.ncbi.nlm.nih.gov/pubmed/32076030 http://dx.doi.org/10.1038/s41598-020-59789-4 |
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