Short-term supplementation of celecoxib-shifted butyrate production on a simulated model of the gut microbial ecosystem and ameliorated in vitro inflammation

Celecoxib has been effective in the prevention and treatment of chronic inflammatory disorders through inhibition of altered cyclooxygenase-2 (COX-2) pathways. Despite the benefits, continuous administration may increase risk of cardiovascular events. Understanding microbiome-drug-host interactions...

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Detalles Bibliográficos
Autores principales: Hernandez-Sanabria, Emma, Heiremans, Evelien, Calatayud Arroyo, Marta, Props, Ruben, Leclercq, Laurent, Snoeys, Jan, Van de Wiele, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031363/
https://www.ncbi.nlm.nih.gov/pubmed/32075981
http://dx.doi.org/10.1038/s41522-020-0119-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031363/
https://www.ncbi.nlm.nih.gov/pubmed/32075981
http://dx.doi.org/10.1038/s41522-020-0119-0

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