Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

Neoantigen burden is regarded as a fundamental determinant of response to immunotherapy. However, its predictive value remains in question because some tumours with high neoantigen load show resistance. Here, we investigate our patient cohort together with a public cohort by our algorithms for the m...

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Detalles Bibliográficos
Autores principales: Kim, Kwoneel, Kim, Hong Sook, Kim, Jeong Yeon, Jung, Hyunchul, Sun, Jong-Mu, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Lee, Se-Hoon, Choi, Jung Kyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031381/
https://www.ncbi.nlm.nih.gov/pubmed/32075964
http://dx.doi.org/10.1038/s41467-020-14562-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031381/
https://www.ncbi.nlm.nih.gov/pubmed/32075964
http://dx.doi.org/10.1038/s41467-020-14562-z

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