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Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype
Alzheimer disease (AD) is a chronic neurodegenerative disease with a multitude of contributing genetic factors, many of which are related to inflammation. The apolipoprotein E (APOE) ε4 allele is the most common genetic risk factor for AD and is related to a pro-inflammatory state. To test the hypot...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031423/ https://www.ncbi.nlm.nih.gov/pubmed/32076055 http://dx.doi.org/10.1038/s41598-020-59869-5 |