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Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype

Alzheimer disease (AD) is a chronic neurodegenerative disease with a multitude of contributing genetic factors, many of which are related to inflammation. The apolipoprotein E (APOE) ε4 allele is the most common genetic risk factor for AD and is related to a pro-inflammatory state. To test the hypot...

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Detalles Bibliográficos
Autores principales:	Friedberg, Jacob S., Aytan, Nurgul, Cherry, Jonathan D., Xia, Weiming, Standring, Oliver J., Alvarez, Victor E., Nicks, Raymond, Svirsky, Sarah, Meng, Gaoyuan, Jun, Gyungah, Ryu, Hoon, Au, Rhoda, Stein, Thor D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031423/ https://www.ncbi.nlm.nih.gov/pubmed/32076055 http://dx.doi.org/10.1038/s41598-020-59869-5

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