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Cysteine redox state regulates human β2-adrenergic receptor binding and function
Bronchoconstrictive airway disorders such as asthma are characterized by inflammation and increases in reactive oxygen species (ROS), which produce a highly oxidative environment. β2-adrenergic receptor (β2AR) agonists are a mainstay of clinical therapy for asthma and provide bronchorelaxation upon...
Autores principales: | Rambacher, Kalyn M., Moniri, Nader H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031529/ https://www.ncbi.nlm.nih.gov/pubmed/32076070 http://dx.doi.org/10.1038/s41598-020-59983-4 |
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