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LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina

The first retinal synapse, photoreceptor→bipolar cell (BC), is both anatomically and functionally complex. Within the same synaptic region, a change in presynaptic glutamate release is sensed by both ON BCs (DBCs) via the metabotropic glutamate receptor 6 (mGluR6), and OFF BCs (HBCs) via ionotropic...

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Detalles Bibliográficos
Autores principales: Hasan, Nazarul, Pangeni, Gobinda, Ray, Thomas A., Fransen, Kathryn M., Noel, Jennifer, Borghuis, Bart G., McCall, Maureen A., Gregg, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031853/
https://www.ncbi.nlm.nih.gov/pubmed/31959619
http://dx.doi.org/10.1523/ENEURO.0002-20.2020