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Circulating 27-hydroxycholesterol and breast cancer tissue expression of CYP27A1, CYP7B1, LXR-β, and ERβ: results from the EPIC-Heidelberg cohort

BACKGROUND: Experimental and epidemiological studies demonstrate a role for 27-hydroxycholesterol (27HC) in breast cancer development, though results are conflicting. Cholesterol 27-hydroxylase (CYP27A1) and oxysterol 7-alpha-hydroxylase (CYP7B1) regulate 27HC concentrations, while differential expr...

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Detalles Bibliográficos
Autores principales:	Le Cornet, Charlotte, Walter, Britta, Sookthai, Disorn, Johnson, Theron S., Kühn, Tilman, Herpel, Ester, Kaaks, Rudolf, Fortner, Renée T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031866/ https://www.ncbi.nlm.nih.gov/pubmed/32075687 http://dx.doi.org/10.1186/s13058-020-1253-6

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