Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses

Herpes Simplex Virus type 1 (HSV-1) chronically infects over 70 per cent of the global population. Clinical manifestations are largely restricted to recurrent epidermal vesicles. However, HSV-1 also leads to encephalitis, the infection of the brain parenchyma, with high associated rates of mortality...

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Detalles Bibliográficos
Autores principales: Lassalle, Florent, Beale, Mathew A, Bharucha, Tehmina, Williams, Charlotte A, Williams, Rachel J, Cudini, Juliana, Goldstein, Richard, Haque, Tanzina, Depledge, Daniel P, Breuer, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031915/
https://www.ncbi.nlm.nih.gov/pubmed/32099667
http://dx.doi.org/10.1093/ve/veaa012

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