Inhibition of microRNA-15 protects H9c2 cells against CVB3-induced myocardial injury by targeting NLRX1 to regulate the NLRP3 inflammasome

BACKGROUND: Viral myocarditis (VMC) is a type of cardiac inflammation that is generally caused by coxsackievirus B3 (CVB3) infection. Several MicroRNAs (miRNAs) are known to play crucial roles in VMC pathogenesis. MiR-15 is reportedly associated with myocardial injury, inflammatory responses and vir...

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Detalles Bibliográficos
Autores principales: Tong, Ru, Jia, Tiewen, Shi, Ruijie, Yan, Futang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031959/
https://www.ncbi.nlm.nih.gov/pubmed/32099552
http://dx.doi.org/10.1186/s11658-020-00203-2

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