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Effects of ordered mutations on dynamics in signaling networks

BACKGROUND: Many previous clinical studies have found that accumulated sequential mutations are statistically related to tumorigenesis. However, they are limited in fully elucidating the significance of the ordered-mutation because they did not focus on the network dynamics. Therefore, there is a pr...

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Detalles Bibliográficos
Autores principales: Mazaya, Maulida, Trinh, Hung-Cuong, Kwon, Yung-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032007/
https://www.ncbi.nlm.nih.gov/pubmed/32075651
http://dx.doi.org/10.1186/s12920-019-0651-z