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Effects of ordered mutations on dynamics in signaling networks
BACKGROUND: Many previous clinical studies have found that accumulated sequential mutations are statistically related to tumorigenesis. However, they are limited in fully elucidating the significance of the ordered-mutation because they did not focus on the network dynamics. Therefore, there is a pr...
Autores principales: | Mazaya, Maulida, Trinh, Hung-Cuong, Kwon, Yung-Keun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032007/ https://www.ncbi.nlm.nih.gov/pubmed/32075651 http://dx.doi.org/10.1186/s12920-019-0651-z |
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