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Optimizing pH-sensitive and time-dependent polymer formula of colonic pH-responsive pellets to achieve precise drug release
Time-sensitive and pH-dependent polymers are generally employed to prepare colon-site delivery system, and their coating thickness and order are very important in controlling the drug release. The traditional colon-site delivery systems consist of time-dependent polymers as inner layer and pH-sensit...
Autores principales: | Song, Lijun, Liang, Liping, Shi, Xiaoying, Chen, Honglang, Zhao, Shumin, Chen, Wenfeng, Zhou, Ruoxia, Zhao, Wenchang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032081/ https://www.ncbi.nlm.nih.gov/pubmed/32104470 http://dx.doi.org/10.1016/j.ajps.2018.05.012 |
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