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The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon

PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance (ABC) upon repeat...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Zhou, Songlei, Kang, Le, Luo, Xiang, Liu, Yang, Song, Yanzhi, Liu, Xinrong, Deng, Yihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2017
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032097/ https://www.ncbi.nlm.nih.gov/pubmed/32104322 http://dx.doi.org/10.1016/j.ajps.2016.06.005

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