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Pharmacokinetics of a ternary conjugate based pH-responsive 10-HCPT prodrug nano-micelle delivery system

A pH-responsive conjugate based 10-hydroxycamptothecin-thiosemicarbazide-polyethene glycol 2000 (10-HCPT-hydro-PEG) nano-micelles were prepared in our previous study. In the present study, ultra-performance liquid chromatography (UPLC-MS) method is developed to investigate its pharmacokinetics and b...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Li, Juan, Li, Zhi, Tang, Xing, Zhang, Zhenzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2017
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032114/ https://www.ncbi.nlm.nih.gov/pubmed/32104367 http://dx.doi.org/10.1016/j.ajps.2017.05.005

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