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In vitro/vivo assessment of praziquantel nanocrystals: Formulation, characterization, and pharmacokinetics in beagle dogs

To investigate the impact of particle size on in vitro/vivo performance of praziquantel (PZQ), nanocrystals (NCs) and microcrystals (MCs) of PZQ were prepared using the methods of wet milling and jet milling, respectively. PZQ NCs and MCs were characterized with dynamic light scattering, laser parti...

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Detalles Bibliográficos
Autores principales:	Yang, Ruyi, Zhang, Tao, Yu, Jiang, Liu, Yan, Wang, Yingli, He, Zhonggui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032129/ https://www.ncbi.nlm.nih.gov/pubmed/32104462 http://dx.doi.org/10.1016/j.ajps.2018.06.001

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