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Bioenhanced advanced third generation solid dispersion of tadalafil: Repurposing with improved therapy in pyelonephritis

Tadalafil (TDL) a BCS-II drug is recently reported for repurposing nephroprotective effect in Pyelonephritis (PN). However, poor water solubility and dissolution rate limited oral bioavailability pose serious challenges in its therapeutic applications. We present an advanced third generation Solid D...

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Detalles Bibliográficos
Autores principales: Mande, Prashant P., Bachhav, Sagar S., Devarajan, Padma V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032132/
https://www.ncbi.nlm.nih.gov/pubmed/32104370
http://dx.doi.org/10.1016/j.ajps.2017.07.001