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Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug()
The purpose of the present study was to investigate the interaction of Cinnarizine (CIN) with Hydroxypropyl-β-Cyclodextrin (HPβCD) in the presence of Hydroxy Acids (HA). Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation methods. For the ternary s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shenyang Pharmaceutical University
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032147/ https://www.ncbi.nlm.nih.gov/pubmed/32104443 http://dx.doi.org/10.1016/j.ajps.2018.02.007 |